PhD Andreas Vegge – University of Copenhagen

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Food, Fitness & Pharma > Scientists > PhD's from UNIK > PhD Andreas Vegge

PhD Andreas Vegge

Department of Nutrition , Exercise and Sports

Affiliated with project no. 3

Title of thesis: Treatment of neonatal short bowel syndrome - lessons from animal models - development, treatment and translation

Thesis summary: The field of clinical neonatology has advanced dramatically over the last decades. The number of premature neonates (<37 weeks of gestation) is increasing and these infants often need intensive clinical support and neonatal clinics are now faced with a new set of clinical challenges. The last organ systems to mature during gestation are the respiratory system and the gastrointestinal tract, and the rapid transition to enteral nutrition constitutes a significant challenge to the preterm gut and it may lead to gastrointestinal complications. The most serious gastrointestinal complication is necrotizing enterocolitis, which is a detrimental inflammatory condition that can occur in preterm infants after the introduction of enteral nutrition. Necrotizing enterocolitis can lead to surgical intervention usually resulting in intestinal resection and the establishment of a stoma, and possibly short bowel syndrome as a result of the loss of absorptive area. The aim of this PhD study has been to develop novel and clinically relevant animal models of a compromised gastrointestinal function in early life.

Publications

Andreas Vegge at PubMed

Links

Andreas Vegge at LinkedIn